Inspired by the above thread, I use the following way to choose different signature based on the recipient's address. send-hook . "set signature=.signature" send-hook "~t mutt-users@xxxxxxxx" "set signature=.mutt/ml-signature" Hope this is usefull. -- Shaochun Wang <xxxx@xxxxxxxxx> My web site: http://lcs.ios.ac.cn/~scwang