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[IP] [SupportTGen] Breaking News from TGen]





Begin forwarded message:

From: bobr@xxxxxxxxxxxxxxxxxxxxxxxxxx
Date: October 19, 2006 8:28:18 PM EDT
To: dave@xxxxxxxxxx
Subject: [Fwd: [SupportTGen] Breaking News from TGen]

Dave

Perhaps for IP.

Exciting news from Phoenix!

I'm personally excited because in addition to having supplied a blood sample to the Banner Alzheimer's Institute, and Mayo Clinic Scottsdale collaboration, both my
father & his father had Alzheimer's (so, you know what my concerns are)!

Now, that light at the end of my tunnel may well be something other than an
onrushing train!

Bob Rosenberg
P.O. Box 33023
Phoenix, AZ  85067-3023
Mobile:  602-206-2856
LandLine:  602-274-3012
bob@xxxxxxxxxxxxxxxxxxxxxxxxxx



--------------------------------- Original Message ---------------------------------
Subject: [SupportTGen] Breaking News from TGen
From:    supporttgen@xxxxxxxxxxxxx
Date:    Thu, October 19, 2006 11:57 am
To:      supporttgen@xxxxxxxxxxxxx
------------------------------------------------------------------------ ------------

Dear TGen supporters and friends:

I am pleased to inform you that researchers at the Translational Genomics Research Institute (TGen) will announce today the discovery of a gene that plays a significant role in memory performance in humans. The findings, reported by TGen and research colleagues at the University of Zurich in Switzerland, Banner Alzheimer's Institute, and Mayo Clinic Scottsdale, will appear in tomorrow's (October 20th) issue of Science. Several local and national media have already shown interest in covering this announcement, including a local CBS News piece airing tonight on KPHO Channel 5, the Phoenix Business Journal, New York Newsday, the Wall Street Journal
and others.

The study details how researchers associated memory performance with a gene called Kibra in over 1,000 individuals. The memory discovery was made by comparing the genetic blueprint of people with good memory to people with poor memory; memory performance was based on a series of gold-standard tests for all individuals. The researchers then validated their discovery by replicating the Kibra gene finding in
two separate and distinct groups of subjects.

Besides the fact that it gives the research community a new and important handhold into truly understanding the process of memory, the Kibra gene is likely a modifier of severity of several other disorders, including Alzheimer's disease, Parkinson's disease, epilepsy, memory loss due to chemotherapy treatments, and others. The ramifications of this report are that scientists may ultimately be able to develop new and effective medicines that can combat memory loss, and that might also help
improve memory in people with memory disorders like Alzheimer's disease.

The team has already begun working on new drugs to restore memory function in
age-related memory loss and diseases that have a memory loss component.

If you'd like additional information, please feel free to contact me.

Michael Bassoff
President, TGen Foundation
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